RAF Typhoon jets have operated alongside French aircraft in a combined operation targeting an hidden munitions depot in Syria operated by the IS group, as stated by the UK's MoD.
The location, identified by intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was located in mountainous terrain just to the north of the historic site of Palmyra in Syria's central region.
"Our fighter planes used laser-guided Paveway IV weapons to target a number of approach shafts providing entry to the facility... initial indications indicate the target was engaged successfully," officials stated.
There was no sign of any civilian impact in the strike on Saturday evening and all the aircraft returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
Daesh - also known as Daesh - established militant control over large swathes of both Syria and Iraq before its territorial defeat in 2019.
"This action demonstrates the UK's leading role, and determination to operate in unison with allied nations, to eliminate any re-emergence of IS and their dangerous and violent ideologies in the area," the British Defence Secretary the minister remarked.
UK warplanes have conducted surveillance missions over Syria to "prevent any efforts to regroup" of IS following its defeat at the battle of Baghuz in 2019, the MoD reported.
"I must thank every member of the UK armed forces who took part in this operation for their professionalism and their bravery," Healey said. "Including them were numerous British troops stationed over the holidays. This mission, to take out dangerous terrorists who threaten our security, demonstrates how UK forces are prepared to act, continuously, protecting the UK within its borders and influential overseas."
Last December, the United States armed forces conducted what it called a "large-scale strike" against Daesh sites in Syria, subsequent to an attack resulted in the deaths of two American soldiers and a civilian linguist in the Palmyra area.
The United Nations reports Daesh still has roughly 5-7 thousand combatants in Syria and Iraq.